Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function

OBJECTIVE: Fibrotic organ responses have recently been identified as long-term complications in diabetes. Indeed, insulin resistance and aberrant hepatic lipid accumulation represent driving features of progressive non-alcoholic fatty liver disease (NAFLD), ranging from simple steatosis and non-alco...

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Detalles Bibliográficos
Autores principales: Wolff, Gretchen, Sakurai, Minako, Mhamane, Amit, Troullinaki, Maria, Maida, Adriano, Deligiannis, Ioannis K., Yin, Kelvin, Weber, Peter, Morgenstern, Jakob, Wieder, Annika, Kwon, Yun, Sekar, Revathi, Zeigerer, Anja, Roden, Michael, Blüher, Matthias, Volk, Nadine, Poth, Tanja, Hackert, Thilo, Wiedmann, Lena, De Angelis Rigotti, Francesca, Rodriguez-Vita, Juan, Fischer, Andreas, Mukthavaram, Rajesh, Limphong, Pattraranee, Tachikawa, Kiyoshi, Karmali, Priya, Payne, Joseph, Chivukula, Padmanabh, Ekim-Üstünel, Bilgen, Martinez-Jimenez, Celia P., Szendrödi, Julia, Nawroth, Peter, Herzig, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034319/
https://www.ncbi.nlm.nih.gov/pubmed/35378329
http://dx.doi.org/10.1016/j.molmet.2022.101487

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