Cargando…

Long chain sphingomyelin depletes cholesterol from the cytoplasmic leaflet in asymmetric lipid membranes

The transbilayer distribution of cholesterol (CHL) in complex asymmetric lipid membranes remains controversial, with contrasting investigations suggesting that there is more CHL either in the exoplasmic, outer leaflet (OL) or the cytoplasmic, inner leaflet (IL) depending on cell type or model, membr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karlsen, Maria Lyngby, Bruhn, Dennis S., Pezeshkian, Weria, Khandelia, Himanshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034350/ https://www.ncbi.nlm.nih.gov/pubmed/35480443 http://dx.doi.org/10.1039/d1ra01464a

Ejemplares similares

Structure and Interdigitation of Chain-Asymmetric Phosphatidylcholines and Milk Sphingomyelin in the Fluid Phase
por: Frewein, Moritz P. K., et al.
Publicado: (2021)

Intermolecular interaction of phosphatidylinositol with the lipid raft molecules sphingomyelin and cholesterol
por: Kinoshita, Masanao, et al.
Publicado: (2008)

Simulations of Asymmetric Membranes Illustrate Cooperative Leaflet Coupling and Lipid Adaptability
por: Blumer, Madison, et al.
Publicado: (2020)

Cholera toxin B subunit induces local curvature on lipid bilayers
por: Pezeshkian, Weria, et al.
Publicado: (2017)

The role of cholesterol-sphingomyelin membrane nanodomains in the stability of intercellular membrane nanotubes
por: Lokar, Maruša, et al.
Publicado: (2012)

HIV-1 Gag targeting to the plasma membrane reorganizes sphingomyelin-rich and cholesterol-rich lipid domains
por: Tomishige, Nario, et al.
Publicado: (2023)

Effect of dietary sphingomyelin on absorption and fractional synthetic rate of cholesterol and serum lipid profile in humans
por: Ramprasath, Vanu R, et al.
Publicado: (2013)

Depletion of Host and Viral Sphingomyelin Impairs Influenza Virus Infection
por: Audi, Amani, et al.
Publicado: (2020)

Triglyceride Blisters in Lipid Bilayers: Implications for Lipid Droplet Biogenesis and the Mobile Lipid Signal in Cancer Cell Membranes
por: Khandelia, Himanshu, et al.
Publicado: (2010)

Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes
por: Kinnebrew, Maia, et al.
Publicado: (2021)

Emphatic visualization of sphingomyelin-rich domains by inter-lipid FRET imaging using fluorescent sphingomyelins
por: Kinoshita, Masanao, et al.
Publicado: (2017)

Sphingomyelin synthase overexpression increases cholesterol accumulation and decreases cholesterol secretion in liver cells
por: Yan, Nianlong, et al.
Publicado: (2011)

A Multi-Scale Approach to Membrane Remodeling Processes
por: Pezeshkian, Weria, et al.
Publicado: (2019)

Backmapping triangulated surfaces to coarse-grained membrane models
por: Pezeshkian, Weria, et al.
Publicado: (2020)

Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer
Publicado: (1993)

Tracking Cholesterol/Sphingomyelin-Rich Membrane Domains with the Ostreolysin A-mCherry Protein
por: Skočaj, Matej, et al.
Publicado: (2014)

The activity of the saponin ginsenoside Rh2 is enhanced by the interaction with membrane sphingomyelin but depressed by cholesterol
por: Verstraeten, Sandrine L., et al.
Publicado: (2019)

Dietary Sphingomyelin Lowers Hepatic Lipid Levels and Inhibits Intestinal Cholesterol Absorption in High-Fat-Fed Mice
por: Chung, Rosanna W. S., et al.
Publicado: (2013)

Strength in numbers: effect of protein crowding on the shape of cell membranes
por: Ruhoff, Victoria Thusgaard, et al.
Publicado: (2022)

Evidence for Segregation of Sphingomyelin and Cholesterol during Formation of Copi-Coated Vesicles
por: Brügger, Britta, et al.
Publicado: (2000)

Characterization of the ordered phase formed by sphingomyelin analogues and cholesterol binary mixtures
por: Kinoshita, Masanao, et al.
Publicado: (2013)

Milk polar lipids reduce lipid cardiovascular risk factors in overweight postmenopausal women: towards a gut sphingomyelin-cholesterol interplay
por: Vors, Cécile, et al.
Publicado: (2020)

Capturing Membrane Phase Separation by Dual Resolution Molecular Dynamics Simulations
por: Liu, Yang, et al.
Publicado: (2021)

Cholesterol binding to the sterol-sensing region of Niemann Pick C1 protein confines dynamics of its N-terminal domain
por: Dubey, Vikas, et al.
Publicado: (2020)

Sphingomyelin and GM1 Influence Huntingtin Binding to, Disruption of, and Aggregation on Lipid Membranes
por: Chaibva, Maxmore, et al.
Publicado: (2018)

Membrane Sphingomyelin in Host Cells Is Essential for Nucleocapsid Penetration into the Cytoplasm after Hemifusion during Rubella Virus Entry
por: Mori, Yoshio, et al.
Publicado: (2022)

Computational Approaches to Explore Bacterial Toxin Entry into the Host Cell
por: Pezeshkian, Weria, et al.
Publicado: (2021)

Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine
por: Maekawa, Masashi, et al.
Publicado: (2016)

A mirror code for protein-cholesterol interactions in the two leaflets of biological membranes
por: Fantini, Jacques, et al.
Publicado: (2016)

Evaluation of the available cholesterol concentration in the inner leaflet of the plasma membrane of mammalian cells
por: Buwaneka, Pawanthi, et al.
Publicado: (2021)

Cholesterol Induces Uneven Curvature of Asymmetric Lipid Bilayers
por: Yesylevskyy, S. O., et al.
Publicado: (2013)

Optimization of Giant Unilamellar Vesicle Electroformation for Phosphatidylcholine/Sphingomyelin/Cholesterol Ternary Mixtures
por: Boban, Zvonimir, et al.
Publicado: (2022)

Water Permeability of Asymmetric Planar Lipid Bilayers: Leaflets of Different Composition Offer Independent and Additive Resistances to Permeation
por: Krylov, Andrey V., et al.
Publicado: (2001)

ON THE COMPONENTS OF SPHINGOMYELIN
por: Levene, P. A.
Publicado: (1913)

Sphingomyelin-Rich Lipid Extract Collar for Canine Atopic Dermatitis
por: Segarra, Sergi, et al.
Publicado: (2023)

Engineered Lipidic Nanomaterials Inspired by Sphingomyelin Metabolism for Cancer Therapy
por: Zhu, Han, et al.
Publicado: (2023)

Communication between the leaflets of asymmetric membranes revealed from coarse-grain molecular dynamics simulations
por: Shearer, Jonathan, et al.
Publicado: (2018)

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol
por: Zalloua, Pierre, et al.
Publicado: (2019)

A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation
por: Takahashi, Kanoko, et al.
Publicado: (2021)

Cholesterol and Sphingomyelin Polarize at the Leading Edge of Migrating Myoblasts and Involve Their Clustering in Submicrometric Domains
por: Vanderroost, Juliette, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_v2rt3m6k8lm0nfut0ibssiecr9