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IFI16 induces inflammation in hepatitis B virus-associated glomerulonephritis by regulating the Caspase-1/ IL-1 ß pathway

AIMS AND BACKGROUND: IFI16 plays an important role in innate immunity against invasive microbial infection by sensing double-stranded DNA viruses due to caspase-1-dependent inflammasome activation and subsequent maturation and secretion of IL-1β. However, the role of IFI16 in regulating the immune r...

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Detalles Bibliográficos
Autores principales:	Liu, Li, Xie, Shuangshuang, Li, Cheng, Guo, Yue, Liu, Xiaoyan, Zhao, Xiuhua, Li, Qiang, Du, Wenjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034479/ https://www.ncbi.nlm.nih.gov/pubmed/35459254 http://dx.doi.org/10.1186/s13000-022-01220-9

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