Cargando…

A Bayesian framework to integrate multi-level genome-scale data for Autism risk gene prioritization

BACKGROUND: Autism spectrum disorder (ASD) is a group of complex neurodevelopment disorders with a strong genetic basis. Large scale sequencing studies have identified over one hundred ASD risk genes. Nevertheless, the vast majority of ASD risk genes remain to be discovered, as it is estimated that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ji, Ying, Chen, Rui, Wang, Quan, Wei, Qiang, Tao, Ran, Li, Bingshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034518/ https://www.ncbi.nlm.nih.gov/pubmed/35459094 http://dx.doi.org/10.1186/s12859-022-04616-y

Ejemplares similares

A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data
por: Wang, Quan, et al.
Publicado: (2019)

Integration of multidimensional splicing data and GWAS summary statistics for risk gene discovery
por: Ji, Ying, et al.
Publicado: (2022)

Leveraging Gene-Level Prediction as Informative Covariate in Hypothesis Weighting Improves Power for Rare Variant Association Studies
por: Ji, Ying, et al.
Publicado: (2022)

Génie: literature-based gene prioritization at multi genomic scale
por: Fontaine, Jean-Fred, et al.
Publicado: (2011)

Integrating multiple protein-protein interaction networks to prioritize disease genes: a Bayesian regression approach
por: Zhang, Wangshu, et al.
Publicado: (2011)

Integrative genomic analyses for identification and prioritization of long non-coding RNAs associated with autism
por: Gudenas, Brian L., et al.
Publicado: (2017)

Prioritization of Copy Number Variation Loci Associated with Autism from AutDB–An Integrative Multi-Study Genetic Database
por: Menashe, Idan, et al.
Publicado: (2013)

IW-Scoring: an Integrative Weighted Scoring framework for annotating and prioritizing genetic variations in the noncoding genome
por: Wang, Jun, et al.
Publicado: (2018)

Gene prioritization using Bayesian matrix factorization with genomic and phenotypic side information
por: Zakeri, Pooya, et al.
Publicado: (2018)

MultiNEP: a multi-omics network enhancement framework for prioritizing disease genes and metabolites simultaneously
por: Xu, Zhuoran, et al.
Publicado: (2023)

DomainRBF: a Bayesian regression approach to the prioritization of candidate domains for complex diseases
por: Zhang, Wangshu, et al.
Publicado: (2011)

Prioritization of therapeutic targets for dyslipidemia using integrative multi-omics and multi-trait analysis
por: Kim, Min Seo, et al.
Publicado: (2023)

Network-based integration of multi-omics data for prioritizing cancer genes
por: Dimitrakopoulos, Christos, et al.
Publicado: (2018)

Prioritization of risk genes in multiple sclerosis by a refined Bayesian framework followed by tissue-specificity and cell type feature assessment
por: Liu, Andi, et al.
Publicado: (2022)

A Parametric Empirical Bayesian Framework for the EEG/MEG Inverse Problem: Generative Models for Multi-Subject and Multi-Modal Integration
por: Henson, Richard N., et al.
Publicado: (2011)

BioModelKit – An Integrative Framework for Multi-Scale Biomodel-Engineering
por: Blätke, Mary-Ann
Publicado: (2018)

Prioritizing disease genes with an improved dual label propagation framework
por: Zhang, Yaogong, et al.
Publicado: (2018)

An Integrative Computational Approach for Prioritization of Genomic Variants
por: Dubchak, Inna, et al.
Publicado: (2014)

A Bayesian framework to update scaling factors for radioactive waste characterization
por: Zaffora, Biagio, et al.
Publicado: (2020)

An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets
por: Ramos, Pablo Ivan Pereira, et al.
Publicado: (2018)

Integrating human omics data to prioritize candidate genes
por: Chen, Yong, et al.
Publicado: (2013)

Ranking and Prioritization for Multi-indicator Systems
por: Brüggemann, Rainer, et al.
Publicado: (2011)

Correction: An Integrative Computational Approach for Prioritization of Genomic Variants
Publicado: (2015)

An Automated Bayesian Framework for Integrative Gene Expression Analysis and Predictive Medicine
por: Parikh, Neena, et al.
Publicado: (2012)

Multi-Scale Graph Representation Learning for Autism Identification With Functional MRI
por: Chu, Ying, et al.
Publicado: (2022)

Evaluation of Rice Degree of Milling Based on Bayesian Optimization and Multi-Scale Residual Model
por: Chen, Weidong, et al.
Publicado: (2022)

A Bayesian Framework to Optimize Performance of Pre-Hospital Stroke Triage Scales
por: Goyal, Mayank, et al.
Publicado: (2021)

DRAMS: A tool to detect and re-align mixed-up samples for integrative studies of multi-omics data
por: Jiang, Yi, et al.
Publicado: (2020)

Prioritization of schizophrenia risk genes from GWAS results by integrating multi-omics data
por: He, Dan, et al.
Publicado: (2021)

A computational framework for the prioritization of disease-gene candidates
por: Browne, Fiona, et al.
Publicado: (2015)

Clinical trials in otology: Examining trends and framework for prioritization
por: Altshuler, Jake, et al.
Publicado: (2021)

Exposure Prioritization (Ex Priori): A Screening-Level High-Throughput Chemical Prioritization Tool
por: Hubbard, Heidi F., et al.
Publicado: (2022)

Regional Management Units for Marine Turtles: A Novel Framework for Prioritizing Conservation and Research across Multiple Scales
por: Wallace, Bryan P., et al.
Publicado: (2010)

A framework for pathway knowledge driven prioritization in genome‐wide association studies
por: Biswas, Shrayashi, et al.
Publicado: (2020)

Cell Type-Specific Predictive Models Perform Prioritization of Genes and Gene Sets Associated With Autism
por: Guan, Jinting, et al.
Publicado: (2021)

Prioritization of Free-Text Clinical Documents: A Novel Use of a Bayesian Classifier
por: Singh, Mark, et al.
Publicado: (2015)

Quantifying tumor specificity using Bayesian probabilistic modeling for drug target discovery and prioritization
por: Li, Guangyuan, et al.
Publicado: (2023)

Meta-path Based Prioritization of Functional Drug Actions with Multi-Level Biological Networks
por: Yoon, Seyeol, et al.
Publicado: (2019)

Attention in a Bayesian Framework
por: Whiteley, Louise, et al.
Publicado: (2012)

Data integration to prioritize drugs using genomics and curated data
por: Louhimo, Riku, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_57729jjbm974ck650teq9ljmqd