A single point mutation in the Plasmodium falciparum 3′–5′ exonuclease does not alter piperaquine susceptibility

BACKGROUND: The rise in Plasmodium falciparum resistance to dihydroartemisinin–piperaquine (DHA–PPQ) treatment has been documented in the Greater Mekong Subregion with associations with mutations in the P. falciparum chloroquine resistance transporter (pfcrt) and plasmepsin 2 (pfpm2) genes. However,...

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Detalles Bibliográficos
Autores principales: Boonyalai, Nonlawat, Kirativanich, Kirakarn, Thamnurak, Chatchadaporn, Praditpol, Chantida, Vesely, Brian A., Wojnarski, Mariusz, Griesenbeck, John S., Waters, Norman C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034581/
https://www.ncbi.nlm.nih.gov/pubmed/35459163
http://dx.doi.org/10.1186/s12936-022-04148-z

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