PMS2 variant results in loss of ATPase activity without compromising mismatch repair

Hereditary cancer syndromes account for approximately 5%–10% of all diagnosed cancer cases. Lynch syndrome (LS) is an autosomal dominant hereditary cancer condition that predisposes individuals to an elevated lifetime risk for developing colorectal, endometrial, and other cancers. LS results from a...

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Detalles Bibliográficos
Autores principales: D'Arcy, Brandon M., Arrington, Jennifer, Weisman, Justin, McClellan, Steven B., Vandana,  , Yang, Zhengrong, Deivanayagam, Champion, Blount, Jessa, Prakash, Aishwarya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034662/
https://www.ncbi.nlm.nih.gov/pubmed/35189042
http://dx.doi.org/10.1002/mgg3.1908

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