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The E3 Ligase RNF157 Inhibits Lens Epithelial Cell Apoptosis by Negatively Regulating p53 in Age-Related Cataracts

PURPOSE: Age-related cataract (ARC) is a major cause of vision impairment worldwide. The E3 ubiquitin ligase RING finger protein 157 (RNF157) is involved in regulating cell survival and downregulated in human cataractous lens samples. However, the function of RNF157 in cataracts remains unclear. Thi...

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Detalles Bibliográficos
Autores principales:	Qi, Tiantian, Jing, Ruihua, Ma, Bo, Hu, Conghui, Wen, Chan, Shao, Yongping, Pei, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Lens
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034709/ https://www.ncbi.nlm.nih.gov/pubmed/35435923 http://dx.doi.org/10.1167/iovs.63.4.11

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