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Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice

Several cellular pathways contribute to neurodegenerative tauopathy-related disorders. Microglial activation, a major component of neuroinflammation, is an early pathologic hallmark that correlates with cognitive decline, while the unfolded protein response (UPR) contributes to synaptic pathology. S...

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Detalles Bibliográficos
Autores principales:	de Oliveira, Paula, Cella, Claire, Locker, Nicolas, Ravindran, Kiran K. G., Mendis, Agampodi, Wafford, Keith, Gilmour, Gary, Dijk, Derk-Jan, Winsky-Sommerer, Raphaelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034788/ https://www.ncbi.nlm.nih.gov/pubmed/35273086 http://dx.doi.org/10.1523/JNEUROSCI.2162-21.2022

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