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Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40%

BACKGROUND: The aim of the present study is to compare the clinical outcomes between left bundle branch area pacing (LBBaP) and right ventricular septal pacing (RVSP) in patients with percent ventricular pacing (VP%) ≥40%. METHODS: Fifty-four patients with VP% ≥40% were retrospectively studied, incl...

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Autores principales: Liu, Xing, Li, Wenbin, Zhou, Xiaolin, Huang, Haobo, Wang, Lei, Wu, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034894/
https://www.ncbi.nlm.nih.gov/pubmed/35469262
http://dx.doi.org/10.2147/IJGM.S360522
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author Liu, Xing
Li, Wenbin
Zhou, Xiaolin
Huang, Haobo
Wang, Lei
Wu, Mingxing
author_facet Liu, Xing
Li, Wenbin
Zhou, Xiaolin
Huang, Haobo
Wang, Lei
Wu, Mingxing
author_sort Liu, Xing
collection PubMed
description BACKGROUND: The aim of the present study is to compare the clinical outcomes between left bundle branch area pacing (LBBaP) and right ventricular septal pacing (RVSP) in patients with percent ventricular pacing (VP%) ≥40%. METHODS: Fifty-four patients with VP% ≥40% were retrospectively studied, including 33 patients with LBBaP and 21 patients with RVSP. QRS duration (QRSd), interventricular mechanical delay (IVMD) and septal-posterior wall motion delay (SPWMD) were measured to evaluate ventricular synchrony. Heart failure hospitalization (HFH), pacing parameters, and complications were evaluated postoperatively and at follow-ups. RESULTS: The mean follow-up duration of the study participants was 13.80 ± 4.47 months. In the LBBaP group, no significant differences were noted in paced QRSd, IVMD and SPWMD of the LBBaP capture and intrinsic-conduction modes, but the paced QRSd was narrower (QRSd, 110.88 ± 7.37 vs 132.90 ± 14.78 ms, P< 0.0001) and the IVMD and SPWMD were lower when compared with the RVSP group (IVMD, 28.16 ± 4.76 vs 40.28 ± 6.97 ms, P <0.0001; SPWMD, 43.68 ± 26.41 vs 97.94 ± 12.77 ms, P <0.0001). LBBaP was associated with better left ventricular function in comparison with RVSP during follow-ups (LVEDD, 47.09 ± 4.47 vs 51.28 ± 7.58, P = 0.017; LVEF, 64.81± 5.49 vs 60.44 ± 9.28, P = 0.041). Patients with LBBaP had lower occurrences of HFH than patients with RVSP (3.13% vs 27.78%, P = 0.034). Pacing parameters showed no differences between the two groups and remained stable throughout the study period. CONCLUSION: The results of this study suggest that LBBaP may be more suitable for patients requiring long-term high ventricular pacing ratio.
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spelling pubmed-90348942022-04-24 Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40% Liu, Xing Li, Wenbin Zhou, Xiaolin Huang, Haobo Wang, Lei Wu, Mingxing Int J Gen Med Original Research BACKGROUND: The aim of the present study is to compare the clinical outcomes between left bundle branch area pacing (LBBaP) and right ventricular septal pacing (RVSP) in patients with percent ventricular pacing (VP%) ≥40%. METHODS: Fifty-four patients with VP% ≥40% were retrospectively studied, including 33 patients with LBBaP and 21 patients with RVSP. QRS duration (QRSd), interventricular mechanical delay (IVMD) and septal-posterior wall motion delay (SPWMD) were measured to evaluate ventricular synchrony. Heart failure hospitalization (HFH), pacing parameters, and complications were evaluated postoperatively and at follow-ups. RESULTS: The mean follow-up duration of the study participants was 13.80 ± 4.47 months. In the LBBaP group, no significant differences were noted in paced QRSd, IVMD and SPWMD of the LBBaP capture and intrinsic-conduction modes, but the paced QRSd was narrower (QRSd, 110.88 ± 7.37 vs 132.90 ± 14.78 ms, P< 0.0001) and the IVMD and SPWMD were lower when compared with the RVSP group (IVMD, 28.16 ± 4.76 vs 40.28 ± 6.97 ms, P <0.0001; SPWMD, 43.68 ± 26.41 vs 97.94 ± 12.77 ms, P <0.0001). LBBaP was associated with better left ventricular function in comparison with RVSP during follow-ups (LVEDD, 47.09 ± 4.47 vs 51.28 ± 7.58, P = 0.017; LVEF, 64.81± 5.49 vs 60.44 ± 9.28, P = 0.041). Patients with LBBaP had lower occurrences of HFH than patients with RVSP (3.13% vs 27.78%, P = 0.034). Pacing parameters showed no differences between the two groups and remained stable throughout the study period. CONCLUSION: The results of this study suggest that LBBaP may be more suitable for patients requiring long-term high ventricular pacing ratio. Dove 2022-04-19 /pmc/articles/PMC9034894/ /pubmed/35469262 http://dx.doi.org/10.2147/IJGM.S360522 Text en © 2022 Liu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Liu, Xing
Li, Wenbin
Zhou, Xiaolin
Huang, Haobo
Wang, Lei
Wu, Mingxing
Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40%
title Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40%
title_full Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40%
title_fullStr Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40%
title_full_unstemmed Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40%
title_short Clinical Outcomes of Left Bundle Branch Area Pacing in Comparison with Right Ventricular Septal Pacing in Patients with High Ventricular Pacing Ratio ≥40%
title_sort clinical outcomes of left bundle branch area pacing in comparison with right ventricular septal pacing in patients with high ventricular pacing ratio ≥40%
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034894/
https://www.ncbi.nlm.nih.gov/pubmed/35469262
http://dx.doi.org/10.2147/IJGM.S360522
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