Probing the competitive inhibitor efficacy of frog-skin alpha helical AMPs identified against ACE2 binding to SARS-CoV-2 S1 spike protein as therapeutic scaffold to prevent COVID-19

In COVID-19 infection, the SARS-CoV-2 spike protein S1 interacts to the ACE2 receptor of human host, instigating the viral infection. To examine the competitive inhibitor efficacy of broad spectrum alpha helical AMPs extracted from frog skin, a comparative study of intermolecular interactions betwee...

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Detalles Bibliográficos
Autores principales: Sekar, P. Chandra, Srinivasan, E., Chandrasekhar, G., Paul, D. Meshach, Sanjay, G., Surya, S., Kumar, NS. Arun Raj, Rajasekaran, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034900/
https://www.ncbi.nlm.nih.gov/pubmed/35461388
http://dx.doi.org/10.1007/s00894-022-05117-8

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