Physicochemical characterization of the recombinant lectin scytovirin and microbicidal activity of the SD1 domain produced in rice against HIV-1

KEY MESSAGE: Rice-produced SD1 retains its physicochemical properties and provides efficient pre-exposure HIV-1 prophylaxis against infection in vitro. ABSTRACT: Scytovirin (SVN) is an HIV-neutralizing lectin that features two structural domains (SD1 and SD2) that bind to HIV-1 envelope glycoprotein...

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Detalles Bibliográficos
Autores principales: Armario-Najera, Victoria, Blanco-Perera, Amaya, Shenoy, Shilpa R., Sun, Yi, Marfil, Silvia, Muñoz-Basagoiti, Jordana, Perez-Zsolt, Daniel, Blanco, Julià, Izquierdo-Useros, Nuria, Capell, Teresa, O’Keefe, Barry R., Christou, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9034974/
https://www.ncbi.nlm.nih.gov/pubmed/35178612
http://dx.doi.org/10.1007/s00299-022-02834-5

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