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Targeting DRD2 by the antipsychotic drug, penfluridol, retards growth of renal cell carcinoma via inducing stemness inhibition and autophagy-mediated apoptosis

Renal cell carcinoma (RCC) is one of the most lethal genitourinary malignancies with poor prognoses, since it is largely resistant to chemotherapy, radiotherapy, and targeted therapy. The persistence of cancer stem cells (CSCs) is the major cause of treatment failure with RCC. Recent evidence showed...

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Detalles Bibliográficos
Autores principales:	Tung, Min-Che, Lin, Yung-Wei, Lee, Wei-Jiunn, Wen, Yu-Ching, Liu, Yu-Cheng, Chen, Ji-Qing, Hsiao, Michael, Yang, Yi-Chieh, Chien, Ming-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035181/ https://www.ncbi.nlm.nih.gov/pubmed/35461314 http://dx.doi.org/10.1038/s41419-022-04828-3

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