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PINK1 ameliorates acute-on-chronic liver failure by inhibiting apoptosis through mTORC2/AKT signaling

Acute-on-chronic liver failure (ACLF) is a lethal syndrome with a remarkable short-term death rate. Even worse, effective internal medicine therapies are currently lacking. Increasing evidence indicates apoptosis plays a critical role in the progression of liver failure. PINK1 has an essential funct...

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Detalles Bibliográficos
Autores principales: Yin, Xuehong, Xue, Ran, Wu, Jing, Wu, Muchen, Xie, Bangxiang, Meng, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035184/
https://www.ncbi.nlm.nih.gov/pubmed/35461334
http://dx.doi.org/10.1038/s41420-022-01021-5