Cargando…

Signaling cascades in the failing heart and emerging therapeutic strategies

Chronic heart failure is the end stage of cardiac diseases. With a high prevalence and a high mortality rate worldwide, chronic heart failure is one of the heaviest health-related burdens. In addition to the standard neurohormonal blockade therapy, several medications have been developed for chronic...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Xin, Du, Tailai, Long, Tianxin, Liao, Xinxue, Dong, Yugang, Huang, Zhan-Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035186/ https://www.ncbi.nlm.nih.gov/pubmed/35461308 http://dx.doi.org/10.1038/s41392-022-00972-6

Ejemplares similares

Circle the Cardiac Remodeling With circRNAs
por: Yang, Tiqun, et al.
Publicado: (2021)

Loss of m(6)A Methyltransferase METTL5 Promotes Cardiac Hypertrophy Through Epitranscriptomic Control of SUZ12 Expression
por: Han, Yanchuang, et al.
Publicado: (2022)

Cardiac ISL1-Interacting Protein, a Cardioprotective Factor, Inhibits the Transition From Cardiac Hypertrophy to Heart Failure
por: Yan, Youchen, et al.
Publicado: (2022)

The Failing Heart
por: Wells, S. Russell
Publicado: (1907)

Emerging nanomedicine-based therapeutics for hematogenous metastatic cascade inhibition: Interfering with the crosstalk between “seed and soil”
por: Wu, Junyu, et al.
Publicado: (2021)

Dedicated Strategies for Triboson Signals from Cascade Decays of Vector Resonances
por: Agashe, Kaustubh, et al.
Publicado: (2017)

Mending the failing heart
por: Wang, Xiaowei, et al.
Publicado: (2019)

Recovery of the failing heart: emerging approaches and mechanisms in excitation-contraction coupling
por: Ibrahim, Michael, et al.
Publicado: (2014)

A Roadmap for Fixing the Heart: RNA Regulatory Networks in Cardiac Disease
por: Tang, Rong, et al.
Publicado: (2020)

Progress in therapeutic strategies based on cancer lipid metabolism
por: Diao, Xia‐Yao, et al.
Publicado: (2019)

Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities
por: Pastor-Fernández, Gloria, et al.
Publicado: (2020)

Beta-blocker/ACE inhibitor therapy differentially impacts the steady state signaling landscape of failing and non-failing hearts
por: Sorrentino, Andrea, et al.
Publicado: (2022)

ENERGY METABOLISM OF THE FAILING HEART
por: Decherd, George, et al.
Publicado: (1934)

Guiding the failing heart to exercise
por: Gielen, S., et al.
Publicado: (2014)

Arrhythmogenic Remodeling in the Failing Heart
por: Husti, Zoltán, et al.
Publicado: (2021)

Melusin Promotes a Protective Signal Transduction Cascade in Stressed Hearts
por: Sorge, Matteo, et al.
Publicado: (2016)

Role of Nrf2 Signaling Cascade in Breast Cancer: Strategies and Treatment
por: Kumar, Hitesh, et al.
Publicado: (2022)

The Wnt signaling cascade in the pathogenesis of osteoarthritis and related promising treatment strategies
por: Cheng, Jinchao, et al.
Publicado: (2022)

The Emerging Link Between the Complement Cascade and Purinergic Signaling in Stress Hematopoiesis
por: Ratajczak, Mariusz Z., et al.
Publicado: (2018)

Targeted Gene-Silencing Reveals the Functional Significance of Myocardin Signaling in the Failing Heart
por: Torrado, Mario, et al.
Publicado: (2011)

Altered Mitochondrial Metabolism and Mechanosensation in the Failing Heart: Focus on Intracellular Calcium Signaling
por: Cabassi, Aderville, et al.
Publicado: (2017)

Emerging strategies for the improvement of chemotherapy in bladder cancer: Current knowledge and future perspectives
por: Liu, Sen, et al.
Publicado: (2021)

Gender Differences in Electrophysiological Gene Expression in Failing and Non-Failing Human Hearts
por: Ambrosi, Christina M., et al.
Publicado: (2013)

Biophysics of the failing heart: physics and biology of heart muscle
por: Solaro, R, et al.
Publicado: (2013)

Mechanisms of Contraction of the Normal and Failing Heart
por: Goodyer, A. V. N.
Publicado: (1969)

Neuromodulation of the Failing Heart: Lost in Translation?
por: Byku, Mirnela, et al.
Publicado: (2016)

Loss of Metabolic Flexibility in the Failing Heart
por: Karwi, Qutuba G., et al.
Publicado: (2018)

Metabolic Effects of Metformin in the Failing Heart
por: Dziubak, Aleksandra, et al.
Publicado: (2018)

Fibroblasts in the Infarcted, Remodeling, and Failing Heart
por: Humeres, Claudio, et al.
Publicado: (2019)

Bursting dynamics in the normal and failing hearts
por: Bondarenko, Vladimir E., et al.
Publicado: (2017)

Mitochondrial Bioenergetics and Dynamism in the Failing Heart
por: Morciano, Giampaolo, et al.
Publicado: (2021)

Computationally Derived Points of Fragility of a Human Cascade Are Consistent with Current Therapeutic Strategies
por: Luan, Deyan, et al.
Publicado: (2007)

Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies
por: Zarantonello, Alessandra, et al.
Publicado: (2021)

Cascaded Electrochemiluminescence Signal Amplifier for the Detection of Telomerase Activity from Tumor Cells and Tissues
por: Zhao, Zhaoyan, et al.
Publicado: (2018)

Targeting ERK1/2-bim signaling cascades by BH3-mimetic ABT-737 as an alternative therapeutic strategy for oral cancer
por: Shin, Ji-Ae, et al.
Publicado: (2015)

Cardiac damage in athlete’s heart: When the “supernormal” heart fails!
por: Carbone, Andreina, et al.
Publicado: (2017)

Emerging Therapeutic Strategies for Attenuating Tubular EMT and Kidney Fibrosis by Targeting Wnt/β-Catenin Signaling
por: Hu, Lichao, et al.
Publicado: (2022)

Emerging Biomarkers and Therapeutic Strategies for Refractory Bullous Pemphigoid
por: Zhou, Tong, et al.
Publicado: (2021)

Chronic vagus nerve stimulation in patients with heart failure: challenge or failed translation?
por: Wu, Zhihong, et al.
Publicado: (2023)

Emerging Therapeutic Strategies for Limbal Stem Cell Deficiency
por: Dong, Ying, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_ju8mmf2kfnbeig8lk8ordo6pje