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Integrative analysis of eQTL and GWAS summary statistics reveals transcriptomic alteration in Alzheimer brains

BACKGROUND: Large-scale genome-wide association studies have successfully identified many genetic variants significantly associated with Alzheimer’s disease (AD), such as rs429358, rs11038106, rs723804, rs13591776, and more. The next key step is to understand the function of these SNPs and the downs...

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Detalles Bibliográficos
Autores principales:	Varathan, Pradeep, Gorijala, Priyanka, Jacobson, Tanner, Chasioti, Danai, Nho, Kwangsik, Risacher, Shannon L., Saykin, Andrew J., Yan, Jingwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035239/ https://www.ncbi.nlm.nih.gov/pubmed/35461270 http://dx.doi.org/10.1186/s12920-022-01245-5

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