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Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration
BACKGROUND: There is uncertainty about the best approaches for advanced airway management (AAM) and the effectiveness of adrenaline treatments in Out-of-hospital cardiac arrest (OHCA). This study aimed to evaluate whether AAM and adrenaline administration provided by Emergency Medical Service (EMS)...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035244/ https://www.ncbi.nlm.nih.gov/pubmed/35461291 http://dx.doi.org/10.1186/s12913-022-07890-x |
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author | Wang, Yu Zhang, Qun Qu, Guang Bo Fang, Fang Dai, Xiao Kang Yu, Liang Xi Zhang, Hong |
author_facet | Wang, Yu Zhang, Qun Qu, Guang Bo Fang, Fang Dai, Xiao Kang Yu, Liang Xi Zhang, Hong |
author_sort | Wang, Yu |
collection | PubMed |
description | BACKGROUND: There is uncertainty about the best approaches for advanced airway management (AAM) and the effectiveness of adrenaline treatments in Out-of-hospital cardiac arrest (OHCA). This study aimed to evaluate whether AAM and adrenaline administration provided by Emergency Medical Service (EMS) can improve the outcomes of OHCA. METHODS: This study was a prospective analysis of collected data based on OHCA adult patients treated by the EMS in China from January 2019 to December 2020.The patients were divided into AAM group and no AAM group, and into subgroups according to whether adrenaline was used. The outcome was rate of return of spontaneous circulation (ROSC), survival to admission and hospital discharge. RESULTS: 1533 OHCA patients were reported. The probability of ROSC outcome and survival admission in the AAM group was significantly higher, compared with no AAM group. The probability of ROSC outcome in the AAM group increased by 66% (adjusted OR: 1.66, 95%CI, 1.02–2.71). There were no significant differences in outcomes between the adrenaline and no adrenaline groups. The combined treatment of AAM and adrenaline increased the probability of ROSC outcome by 114% (adjusted OR, 2.14, 95%CI, 1.20–3.81) and the probability of survival to admission increased by 115% (adjusted OR, 2.15, 95%CI, 1.16–3.97). CONCLUSIONS: The prehospital AAM and the combined treatment of AAM and adrenaline in OHCA patients are both associated with an increased rate of ROSC. The combined treatment of AAM and adrenaline can improve rate of survival to admission in OHCA patients. |
format | Online Article Text |
id | pubmed-9035244 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-90352442022-04-25 Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration Wang, Yu Zhang, Qun Qu, Guang Bo Fang, Fang Dai, Xiao Kang Yu, Liang Xi Zhang, Hong BMC Health Serv Res Research BACKGROUND: There is uncertainty about the best approaches for advanced airway management (AAM) and the effectiveness of adrenaline treatments in Out-of-hospital cardiac arrest (OHCA). This study aimed to evaluate whether AAM and adrenaline administration provided by Emergency Medical Service (EMS) can improve the outcomes of OHCA. METHODS: This study was a prospective analysis of collected data based on OHCA adult patients treated by the EMS in China from January 2019 to December 2020.The patients were divided into AAM group and no AAM group, and into subgroups according to whether adrenaline was used. The outcome was rate of return of spontaneous circulation (ROSC), survival to admission and hospital discharge. RESULTS: 1533 OHCA patients were reported. The probability of ROSC outcome and survival admission in the AAM group was significantly higher, compared with no AAM group. The probability of ROSC outcome in the AAM group increased by 66% (adjusted OR: 1.66, 95%CI, 1.02–2.71). There were no significant differences in outcomes between the adrenaline and no adrenaline groups. The combined treatment of AAM and adrenaline increased the probability of ROSC outcome by 114% (adjusted OR, 2.14, 95%CI, 1.20–3.81) and the probability of survival to admission increased by 115% (adjusted OR, 2.15, 95%CI, 1.16–3.97). CONCLUSIONS: The prehospital AAM and the combined treatment of AAM and adrenaline in OHCA patients are both associated with an increased rate of ROSC. The combined treatment of AAM and adrenaline can improve rate of survival to admission in OHCA patients. BioMed Central 2022-04-23 /pmc/articles/PMC9035244/ /pubmed/35461291 http://dx.doi.org/10.1186/s12913-022-07890-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visithttp://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Wang, Yu Zhang, Qun Qu, Guang Bo Fang, Fang Dai, Xiao Kang Yu, Liang Xi Zhang, Hong Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration |
title | Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration |
title_full | Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration |
title_fullStr | Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration |
title_full_unstemmed | Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration |
title_short | Effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration |
title_sort | effects of prehospital management in out-of-hospital cardiac arrest: advanced airway and adrenaline administration |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035244/ https://www.ncbi.nlm.nih.gov/pubmed/35461291 http://dx.doi.org/10.1186/s12913-022-07890-x |
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