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AXL regulates neuregulin1 expression leading to cetuximab resistance in head and neck cancer

BACKGROUND: The receptor tyrosine kinase (RTK) epidermal growth factor receptor (EGFR) is overexpressed and an important therapeutic target in Head and Neck cancer (HNC). Cetuximab is currently the only EGFR-targeting agent approved by the FDA for treatment of HNC; however, intrinsic and acquired re...

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Detalles Bibliográficos
Autores principales:	Iida, Mari, McDaniel, Nellie K., Kostecki, Kourtney L., Welke, Noah B., Kranjac, Carlene A., Liu, Peng, Longhurst, Colin, Bruce, Justine Y., Hong, Seungpyo, Salgia, Ravi, Wheeler, Deric L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035247/ https://www.ncbi.nlm.nih.gov/pubmed/35461210 http://dx.doi.org/10.1186/s12885-022-09511-6

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