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A case of multiple abscesses caused by Nocardia farcinica rapidly diagnosed by MALDI-TOF MS

Identifying Nocardia species in routine tests is often difficult owing to its culture time. We report a case of nocardiosis characterized by multiple abscesses of disseminated disease. A man in his 50 's presented with inflammation on the left buttock and right lower leg. Nocardia farcinica was...

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Detalles Bibliográficos
Autores principales: Yonetani, Shota, Ohnishi, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035396/
https://www.ncbi.nlm.nih.gov/pubmed/35479109
http://dx.doi.org/10.1016/j.idcr.2022.e01497
Descripción
Sumario:Identifying Nocardia species in routine tests is often difficult owing to its culture time. We report a case of nocardiosis characterized by multiple abscesses of disseminated disease. A man in his 50 's presented with inflammation on the left buttock and right lower leg. Nocardia farcinica was isolated from the abscess on his buttock and confirmed using matrix-assisted laser desorption/ionization–time of flight mass spectrometry (MALDI-TOF MS). Radiological assessment revealed multiple abscesses in his brain, left lung, and right thigh. He was successfully treated with antibiotics. Accurate species identification by MALDI-TOF MS aids in the optimal treatment of nocardiosis.