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Downregulation of epithelial sodium channel (ENaC) activity in cystic fibrosis cells by epigenetic targeting

The pathogenic mechanism of cystic fibrosis (CF) includes the functional interaction of the cystic fibrosis transmembrane conductance regulator (CFTR) protein with the epithelial sodium channel (ENaC). The reduction of ENaC activity may constitute a therapeutic option for CF. This hypothesis was eva...

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Detalles Bibliográficos
Autores principales:	Blaconà, Giovanna, Raso, Roberto, Castellani, Stefano, Pierandrei, Silvia, Del Porto, Paola, Ferraguti, Giampiero, Ascenzioni, Fiorentina, Conese, Massimo, Lucarelli, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035428/ https://www.ncbi.nlm.nih.gov/pubmed/35462606 http://dx.doi.org/10.1007/s00018-022-04190-9

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