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Modeling the Potential of Treg-Based Therapies for Transplant Rejection: Effect of Dose, Timing, and Accumulation Site
Introduction: The adoptive transfer of regulatory T cells (Tregs) has emerged as a method to promote graft tolerance. Clinical trials have demonstrated the safety of adoptive transfer and are now assessing their therapeutic efficacy. Strategies that generate large numbers of antigen specific Tregs a...
Autores principales: | Lapp, Maya M., Lin, Guang, Komin, Alexander, Andrews, Leah, Knudson, Mei, Mossman, Lauren, Raimondi, Giorgio, Arciero, Julia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035492/ https://www.ncbi.nlm.nih.gov/pubmed/35479106 http://dx.doi.org/10.3389/ti.2022.10297 |
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