Factor XIII is a newly identified binding partner for platelet collagen receptor GPVI‐dimer—An interaction that may modulate fibrin crosslinking

BACKGROUND: In the fibrin‐forming process, thrombin cleaves fibrinogen to fibrin, which form fibrils and then fibers, producing a gel‐like clot. Thrombin also activates coagulation factor XIII (FXIII), which crosslinks fibrin γ‐chains and α‐chains, stabilizing the clot. Many proteins bind to fibrin,...

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Detalles Bibliográficos
Autores principales: Moroi, Masaaki, Induruwa, Isuru, Farndale, Richard W., Jung, Stephanie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035508/
https://www.ncbi.nlm.nih.gov/pubmed/35494504
http://dx.doi.org/10.1002/rth2.12697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035508/
https://www.ncbi.nlm.nih.gov/pubmed/35494504
http://dx.doi.org/10.1002/rth2.12697

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