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Chronic Activation of LXRα Sensitizes Mice to Hepatocellular Carcinoma

The oxysterol receptor liver X receptor (LXR) is a nuclear receptor best known for its function in the regulation of lipid and cholesterol metabolism. LXRs, both the α and β isoforms, have been suggested as potential therapeutic targets for several cancer types. However, there was a lack of report o...

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Detalles Bibliográficos
Autores principales: Xie, Yang, Sun, Runzi, Gao, Li, Guan, Jibin, Wang, Jingyuan, Bell, Aaron, Zhu, Junjie, Zhang, Min, Xu, Meishu, Lu, Peipei, Cai, Xinran, Ren, Songrong, Xu, Pengfei, Monga, Satdarshan P., Ma, Xiaochao, Yang, Da, Liu, Yulan, Lu, Binfeng, Xie, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035576/
https://www.ncbi.nlm.nih.gov/pubmed/34981658
http://dx.doi.org/10.1002/hep4.1880