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Palladium-Mediated Hydroamination of DNA-Conjugated Aryl Alkenes

C-N bond formation is one of the most commonly used reactions in medicinal chemistry. Herein, we report an efficient Pd-promoted hydroamination reaction between DNA-conjugated aryl alkenes and a wide scope of aliphatic amines. The described reactions are demonstrated in good to excellent conversions...

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Detalles Bibliográficos
Autores principales: Cai, Kunliang, Ran, Yuzhao, Sun, Wenbo, Gao, Sen, Li, Jin, Wan, Jinqiao, Liu, Guansai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035600/
https://www.ncbi.nlm.nih.gov/pubmed/35480389
http://dx.doi.org/10.3389/fchem.2022.851674