Periodontitis promotes the expression of gingival transmembrane serine protease 2 (TMPRSS2), a priming protease for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

OBJECTIVES: The oral cavity is one of the main entry sites for SARS-CoV-2. Gingival keratinocytes express transmembrane serine protease 2 (TMPRSS2), responsible for priming the SARS-CoV-2 spike protein. We investigated whether periodontitis increased the expression of TMPRSS2. METHODS: To investigat...

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Detalles Bibliográficos
Autores principales: Ohnishi, Tomokazu, Nakamura, Toshiaki, Shima, Kaori, Noguchi, Kazuyuki, Chiba, Norika, Matsuguchi, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Oral Biology. Published by Elsevier B.V. 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035663/
https://www.ncbi.nlm.nih.gov/pubmed/35472469
http://dx.doi.org/10.1016/j.job.2022.04.004

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