Cargando…

Single-cell atlas of the aging mouse colon

We performed massive single-cell sequencing in the aging mouse colonic epithelium and immune cells. We identified novel compartment-specific markers as well as dramatic aging-associated changes in cell composition and signaling pathways, including a shift from absorptive to secretory epithelial cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Širvinskas, Dovydas, Omrani, Omid, Lu, Jing, Rasa, Mahdi, Krepelova, Anna, Adam, Lisa, Kaeppel, Sandra, Sommer, Felix, Neri, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035718/ https://www.ncbi.nlm.nih.gov/pubmed/35479413 http://dx.doi.org/10.1016/j.isci.2022.104202

Ejemplares similares

Establishment and evaluation of module-based immune-associated gene signature to predict overall survival in patients of colon adenocarcinoma
por: Lu, Jing, et al.
Publicado: (2022)

IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration
por: Omrani, Omid, et al.
Publicado: (2023)

Author Correction: IFNγ-Stat1 axis drives aging-associated loss of intestinal tissue homeostasis and regeneration
por: Omrani, Omid, et al.
Publicado: (2023)

Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
por: Freter, Rasmus, et al.
Publicado: (2021)

Characterization of Novel α-Mangostin and Paeonol Derivatives With Cancer-Selective Cytotoxicity
por: Nunna, Suneetha, et al.
Publicado: (2022)

Characterization of an in vitro 3D intestinal organoid model by using massive RNAseq-based transcriptome profiling
por: Lu, Jing, et al.
Publicado: (2021)

Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius furzeri Skeletal Muscle
por: Cencioni, Chiara, et al.
Publicado: (2019)

Myc and Max Genome-Wide Binding Sites Analysis Links the Myc Regulatory Network with the Polycomb and the Core Pluripotency Networks in Mouse Embryonic Stem Cells
por: Krepelova, Anna, et al.
Publicado: (2014)

Antisense lncRNA CHROMR is linked to glioma patient survival
por: Širvinskas, Dovydas, et al.
Publicado: (2023)

Risk Factors for Delayed Neurocognitive Recovery According to Brain Biomarkers and Cerebral Blood Flow Velocity
por: Bukauskienė, Rasa, et al.
Publicado: (2020)

Genome-wide analysis identifies a functional association of Tet1 and Polycomb repressive complex 2 in mouse embryonic stem cells
por: Neri, Francesco, et al.
Publicado: (2013)

HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration
por: Tapias, Alicia, et al.
Publicado: (2021)

Iron Oxide Nanoparticles Carrying 5-Fluorouracil in Combination with Magnetic Hyperthermia Induce Thrombogenic Collagen Fibers, Cellular Stress, and Immune Responses in Heterotopic Human Colon Cancer in Mice
por: Dabaghi, Mohammad, et al.
Publicado: (2021)

Single-cell transcriptomic atlas of mouse cochlear aging
por: Sun, Guoqiang, et al.
Publicado: (2022)

The effect of relative cerebral hyperperfusion during cardiac surgery with cardiopulmonary bypass to delayed neurocognitive recovery
por: Kasputytė, Greta, et al.
Publicado: (2022)

Do age, diabetes and left ventricular function affect the outcomes of ischemic mitral valve repair?
por: Jankauskiene, Loreta, et al.
Publicado: (2014)

DNMT3B supports meso-endoderm differentiation from mouse embryonic stem cells
por: Lauria, Andrea, et al.
Publicado: (2023)

Determining the International Spread of B.1.1.523 SARS-CoV-2 Lineage with a Set of Mutations Highly Associated with Reduced Immune Neutralization
por: Zemaitis, Lukas, et al.
Publicado: (2022)

DNA methylation modulates allograft survival and acute rejection after renal transplantation by regulating the mTOR pathway
por: Zhu, Chaohong, et al.
Publicado: (2020)

A metabolome atlas of the aging mouse brain
por: Ding, Jun, et al.
Publicado: (2021)

Androgen-Induced MIG6 Regulates Phosphorylation of Retinoblastoma Protein and AKT to Counteract Non-Genomic AR Signaling in Prostate Cancer Cells
por: Schomann, Tim, et al.
Publicado: (2022)

TET1 is controlled by pluripotency-associated factors in ESCs and downmodulated by PRC2 in differentiated cells and tissues
por: Neri, Francesco, et al.
Publicado: (2015)

Goblet cell adenocarcinoma of the ascending colon: An underrecognized diagnostic pitfall
por: Limaiem, Faten, et al.
Publicado: (2023)

Postoperative delirium following cardiac surgery: the incidence, risk factors and outcome
por: Andrejaitiene, Judita, et al.
Publicado: (2015)

Ageing and gastrointestinal sensory function: altered colonic mechanosensory and chemosensory function in the aged mouse
por: Keating, Christopher, et al.
Publicado: (2016)

DNA methylation atlas of the mouse brain at single-cell resolution
por: Liu, Hanqing, et al.
Publicado: (2021)

Colonization, mouse-style
por: Gabriel, Sofia I, et al.
Publicado: (2010)

RADIOGRAPHIC ATLAS OF COLON DISEASE
Publicado: (1981)

Effect of whitening toothpastes containing activated charcoal, abrasive particles, or hydrogen peroxide on the color of aged microhybrid composite
por: Rostamzadeh, Pouya, et al.
Publicado: (2021)

A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors
por: Crowley, Laura, et al.
Publicado: (2020)

Impact of autologous centrifuged shed mediastinal blood on procalcitonin, C-reactive protein levels and postoperative complications during the early period following cardiac surgery
por: Andrejaitiene, Judita, et al.
Publicado: (2007)

A case-control study of readmission to the intensive care unit after cardiac surgery
por: Benetis, Rimantas, et al.
Publicado: (2013)

Single-cell transcriptomic profiling of the mouse cochlea: An atlas for targeted therapies
por: Jean, Philippe, et al.
Publicado: (2023)

Thigh phlegmon as a first sign of a perforated sigmoid colon tumor
por: Hajri, Mohamed, et al.
Publicado: (2022)

Single-cell transcriptomic atlas of primate cardiopulmonary aging
por: Ma, Shuai, et al.
Publicado: (2020)

A single-cell atlas of the aging murine ovary
por: Isola, José V. V., et al.
Publicado: (2023)

Single-cell immune atlas for human aging and frailty
por: Leng, Sean X, et al.
Publicado: (2022)

Selective Ultrasonic Gravimetric Sensors Based on Capacitive Micromachined Ultrasound Transducer Structure—A Review
por: Barauskas, Dovydas, et al.
Publicado: (2020)

Anatomical Transcriptome Atlas of the Male Mouse Reproductive System During Aging
por: Huang, Yanping, et al.
Publicado: (2022)

Traumatic Arteriovenous Malformation of the Superficial Temporal Artery
por: Fard, Mahmoud Omrani, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_msucd51vds8q6br63gnp6aohti