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Multi-modal imaging for uptake of peptide ligand specific for CD44 by hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is rising steadily in incidence, and more effective methods are needed for early cancer detection and image-guided surgery. METHODS: We used a structural model to optimize the peptide sequence. Specific binding was validated in vitro with knockdown, competi...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoli, Meng, Xiaoqing, Chang, Tse-Shao, Feng, Shuo, Lee, Miki, Jaiswal, Sangeeta, Choi, Eun-Young K., Tran, Lam, Jiang, Hui, Wang, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035732/
https://www.ncbi.nlm.nih.gov/pubmed/35479192
http://dx.doi.org/10.1016/j.pacs.2022.100355