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Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone

Whether and how innate antiviral response is regulated by humoral metabolism remains enigmatic. We show that viral infection induces progesterone via the hypothalamic-pituitary-adrenal axis in mice. Progesterone induces downstream antiviral genes and promotes innate antiviral response in cells and m...

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Detalles Bibliográficos
Autores principales:	Su, Shan, Hua, Duo, Li, Jin-Peng, Zhang, Xia-Nan, Bai, Lei, Cao, Li-Bo, Guo, Yi, Zhang, Ming, Dong, Jia-Zhen, Liang, Xiao-Wei, Lan, Ke, Hu, Ming-Ming, Shu, Hong-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035769/ https://www.ncbi.nlm.nih.gov/pubmed/35468896 http://dx.doi.org/10.1038/s41392-022-00981-5

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