Small Heat Shock Proteins in Retinal Diseases

This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks....

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Detalles Bibliográficos
Autores principales: Rajeswaren, Vivian, Wong, Jeffrey O., Yabroudi, Dana, Nahomi, Rooban B., Rankenberg, Johanna, Nam, Mi-Hyun, Nagaraj, Ram H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035800/
https://www.ncbi.nlm.nih.gov/pubmed/35480891
http://dx.doi.org/10.3389/fmolb.2022.860375
Descripción
Sumario:This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed.

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