Small Heat Shock Proteins in Retinal Diseases

This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks....

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Autores principales: Rajeswaren, Vivian, Wong, Jeffrey O., Yabroudi, Dana, Nahomi, Rooban B., Rankenberg, Johanna, Nam, Mi-Hyun, Nagaraj, Ram H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035800/
https://www.ncbi.nlm.nih.gov/pubmed/35480891
http://dx.doi.org/10.3389/fmolb.2022.860375
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author Rajeswaren, Vivian
Wong, Jeffrey O.
Yabroudi, Dana
Nahomi, Rooban B.
Rankenberg, Johanna
Nam, Mi-Hyun
Nagaraj, Ram H.
author_facet Rajeswaren, Vivian
Wong, Jeffrey O.
Yabroudi, Dana
Nahomi, Rooban B.
Rankenberg, Johanna
Nam, Mi-Hyun
Nagaraj, Ram H.
author_sort Rajeswaren, Vivian
collection PubMed
description This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed.
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spelling pubmed-90358002022-04-26 Small Heat Shock Proteins in Retinal Diseases Rajeswaren, Vivian Wong, Jeffrey O. Yabroudi, Dana Nahomi, Rooban B. Rankenberg, Johanna Nam, Mi-Hyun Nagaraj, Ram H. Front Mol Biosci Molecular Biosciences This review summarizes the latest findings on small heat shock proteins (sHsps) in three major retinal diseases: glaucoma, diabetic retinopathy, and age-related macular degeneration. A general description of the structure and major cellular functions of sHsps is provided in the introductory remarks. Their role in specific retinal diseases, highlighting their regulation, role in pathogenesis, and possible use as therapeutics, is discussed. Frontiers Media S.A. 2022-04-11 /pmc/articles/PMC9035800/ /pubmed/35480891 http://dx.doi.org/10.3389/fmolb.2022.860375 Text en Copyright © 2022 Rajeswaren, Wong, Yabroudi, Nahomi, Rankenberg, Nam and Nagaraj. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Molecular Biosciences
Rajeswaren, Vivian
Wong, Jeffrey O.
Yabroudi, Dana
Nahomi, Rooban B.
Rankenberg, Johanna
Nam, Mi-Hyun
Nagaraj, Ram H.
Small Heat Shock Proteins in Retinal Diseases
title Small Heat Shock Proteins in Retinal Diseases
title_full Small Heat Shock Proteins in Retinal Diseases
title_fullStr Small Heat Shock Proteins in Retinal Diseases
title_full_unstemmed Small Heat Shock Proteins in Retinal Diseases
title_short Small Heat Shock Proteins in Retinal Diseases
title_sort small heat shock proteins in retinal diseases
topic Molecular Biosciences
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035800/
https://www.ncbi.nlm.nih.gov/pubmed/35480891
http://dx.doi.org/10.3389/fmolb.2022.860375
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