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MUS81 Inhibition Enhances the Anticancer Efficacy of Talazoparib by Impairing ATR/CHK1 Signaling Pathway in Gastric Cancer

MUS81 is a critical endonuclease involved in heterodimer formation with Eme1/Mms4 and an important DNA damage repair regulatory molecule. Our previous study suggested that MUS81 was overexpressed and its high expression was positively correlated with gastric cancer metastasis. However, the therapeut...

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Detalles Bibliográficos
Autores principales:	Wang, Tao, Zhang, Peng, Li, Chengguo, Liu, Weizhen, Shen, Qian, Yang, Lei, Xie, Gengchen, Bai, Jie, Li, Ruidong, Tao, Kaixiong, Yin, Yuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035870/ https://www.ncbi.nlm.nih.gov/pubmed/35480096 http://dx.doi.org/10.3389/fonc.2022.844135

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