A Cancer Associated Fibroblasts-Related Six-Gene Panel for Anti-PD-1 Therapy in Melanoma Driven by Weighted Correlation Network Analysis and Supervised Machine Learning

BACKGROUND: Melanoma is a highly aggressive skin cancer with a poor prognosis and mortality. Immune checkpoint blockade (ICB) therapy (e.g., anti-PD-1 therapy) has opened a new horizon in melanoma treatment, but some patients present a non-responsive state. Cancer-associated fibroblasts (CAFs) make...

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Detalles Bibliográficos
Autores principales: Tian, Luyao, Long, Fei, Hao, Youjin, Li, Bo, Li, Yinghong, Tang, Ying, Li, Jing, Zhao, Qi, Chen, Juan, Liu, Mingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035939/
https://www.ncbi.nlm.nih.gov/pubmed/35479936
http://dx.doi.org/10.3389/fmed.2022.880326

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