The gut microbiome as a modulator of healthy ageing

The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut mic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghosh, Tarini Shankar, Shanahan, Fergus, O’Toole, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035980/
https://www.ncbi.nlm.nih.gov/pubmed/35468952
http://dx.doi.org/10.1038/s41575-022-00605-x
_version_ 1784693421012680704
author Ghosh, Tarini Shankar
Shanahan, Fergus
O’Toole, Paul W.
author_facet Ghosh, Tarini Shankar
Shanahan, Fergus
O’Toole, Paul W.
author_sort Ghosh, Tarini Shankar
collection PubMed
description The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut microbiome of older individuals and general cohort studies across geographically distinct populations. We also address the promise of the targeted restoration of microorganisms associated with healthier ageing.
format Online
Article
Text
id pubmed-9035980
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-90359802022-04-25 The gut microbiome as a modulator of healthy ageing Ghosh, Tarini Shankar Shanahan, Fergus O’Toole, Paul W. Nat Rev Gastroenterol Hepatol Review Article The gut microbiome is a contributory factor in ageing-related health loss and in several non-communicable diseases in all age groups. Some age-linked and disease-linked compositional and functional changes overlap, while others are distinct. In this Review, we explore targeted studies of the gut microbiome of older individuals and general cohort studies across geographically distinct populations. We also address the promise of the targeted restoration of microorganisms associated with healthier ageing. Nature Publishing Group UK 2022-04-25 2022 /pmc/articles/PMC9035980/ /pubmed/35468952 http://dx.doi.org/10.1038/s41575-022-00605-x Text en © Springer Nature Limited 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Ghosh, Tarini Shankar
Shanahan, Fergus
O’Toole, Paul W.
The gut microbiome as a modulator of healthy ageing
title The gut microbiome as a modulator of healthy ageing
title_full The gut microbiome as a modulator of healthy ageing
title_fullStr The gut microbiome as a modulator of healthy ageing
title_full_unstemmed The gut microbiome as a modulator of healthy ageing
title_short The gut microbiome as a modulator of healthy ageing
title_sort gut microbiome as a modulator of healthy ageing
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035980/
https://www.ncbi.nlm.nih.gov/pubmed/35468952
http://dx.doi.org/10.1038/s41575-022-00605-x
work_keys_str_mv AT ghoshtarinishankar thegutmicrobiomeasamodulatorofhealthyageing
AT shanahanfergus thegutmicrobiomeasamodulatorofhealthyageing
AT otoolepaulw thegutmicrobiomeasamodulatorofhealthyageing
AT ghoshtarinishankar gutmicrobiomeasamodulatorofhealthyageing
AT shanahanfergus gutmicrobiomeasamodulatorofhealthyageing
AT otoolepaulw gutmicrobiomeasamodulatorofhealthyageing

Ejemplares similares