Cargando…

Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022)

Alzheimer's Disease Diagnosis In article number 2104542 by Hye Yun Kim, YoungSoo Kim, and co‐workers, the reliability of blood amyloid‐β (Aβ) as an early diagnostic biomarker for Alzheimer's disease (AD) is demonstrated by stimulation of a brain‐to‐blood efflux of Aβ in AD transgenic mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Donghee, Kim, Hyunjin Vincent, Kim, Hye Yun, Kim, YoungSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035996/
http://dx.doi.org/10.1002/advs.202270078
_version_ 1784693425031872512
author Lee, Donghee
Kim, Hyunjin Vincent
Kim, Hye Yun
Kim, YoungSoo
author_facet Lee, Donghee
Kim, Hyunjin Vincent
Kim, Hye Yun
Kim, YoungSoo
author_sort Lee, Donghee
collection PubMed
description Alzheimer's Disease Diagnosis In article number 2104542 by Hye Yun Kim, YoungSoo Kim, and co‐workers, the reliability of blood amyloid‐β (Aβ) as an early diagnostic biomarker for Alzheimer's disease (AD) is demonstrated by stimulation of a brain‐to‐blood efflux of Aβ in AD transgenic mice through oral administration of a chemical that dissociate amyloid plaques in the brain and a subsequent increase of Aβ concentration to be detected in blood. [Image: see text]
format Online
Article
Text
id pubmed-9035996
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-90359962022-04-27 Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022) Lee, Donghee Kim, Hyunjin Vincent Kim, Hye Yun Kim, YoungSoo Adv Sci (Weinh) Inside Back Cover Alzheimer's Disease Diagnosis In article number 2104542 by Hye Yun Kim, YoungSoo Kim, and co‐workers, the reliability of blood amyloid‐β (Aβ) as an early diagnostic biomarker for Alzheimer's disease (AD) is demonstrated by stimulation of a brain‐to‐blood efflux of Aβ in AD transgenic mice through oral administration of a chemical that dissociate amyloid plaques in the brain and a subsequent increase of Aβ concentration to be detected in blood. [Image: see text] John Wiley and Sons Inc. 2022-04-25 /pmc/articles/PMC9035996/ http://dx.doi.org/10.1002/advs.202270078 Text en © 2022 Wiley‐VCH GmbH https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Inside Back Cover
Lee, Donghee
Kim, Hyunjin Vincent
Kim, Hye Yun
Kim, YoungSoo
Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022)
title Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022)
title_full Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022)
title_fullStr Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022)
title_full_unstemmed Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022)
title_short Chemical‐Driven Outflow of Dissociated Amyloid Burden from Brain to Blood (Adv. Sci. 12/2022)
title_sort chemical‐driven outflow of dissociated amyloid burden from brain to blood (adv. sci. 12/2022)
topic Inside Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9035996/
http://dx.doi.org/10.1002/advs.202270078
work_keys_str_mv AT leedonghee chemicaldrivenoutflowofdissociatedamyloidburdenfrombraintobloodadvsci122022
AT kimhyunjinvincent chemicaldrivenoutflowofdissociatedamyloidburdenfrombraintobloodadvsci122022
AT kimhyeyun chemicaldrivenoutflowofdissociatedamyloidburdenfrombraintobloodadvsci122022
AT kimyoungsoo chemicaldrivenoutflowofdissociatedamyloidburdenfrombraintobloodadvsci122022