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Tumor suppressor BAP1 nuclear import is governed by transportin-1

Subcellular localization of the deubiquitinating enzyme BAP1 is deterministic for its tumor suppressor activity. While the monoubiquitination of BAP1 by an atypical E2/E3-conjugated enzyme UBE2O and BAP1 auto-deubiquitination are known to regulate its nuclear localization, the molecular mechanism by...

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Detalles Bibliográficos
Autores principales:	Yang, Tzu-Jing, Li, Tian-Neng, Huang, Rih-Sheng, Pan, Max Yu-Chen, Lin, Shu-Yu, Lin, Steven, Wu, Kuen-Phon, Wang, Lily Hui-Ching, Hsu, Shang-Te Danny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036092/ https://www.ncbi.nlm.nih.gov/pubmed/35446349 http://dx.doi.org/10.1083/jcb.202201094

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