Gene repression through epigenetic modulation by PPARA enhances hepatocellular proliferation

Peroxisome proliferator-activated receptor α (PPARA) is a key mediator of lipid metabolism and inflammation. Activation of PPARA in rodents causes hepatocyte proliferation, but the underlying mechanism is poorly understood. This study focused on genes repressed by PPARA and analyzed the mechanism by...

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Detalles Bibliográficos
Autores principales: Aibara, Daisuke, Takahashi, Shogo, Yagai, Tomoki, Kim, Donghwan, Brocker, Chad N., Levi, Moshe, Matsusue, Kimihiko, Gonzalez, Frank J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036120/
https://www.ncbi.nlm.nih.gov/pubmed/35479397
http://dx.doi.org/10.1016/j.isci.2022.104196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036120/
https://www.ncbi.nlm.nih.gov/pubmed/35479397
http://dx.doi.org/10.1016/j.isci.2022.104196

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