A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway

BAG1 is a family of polypeptides with a conserved C-terminal BAG domain that functions as a nucleotide exchange factor for the molecular chaperone HSP70. BAG1 proteins also control several signaling processes including proteostasis, apoptosis, and transcription. The largest isoform, BAG1L, controls...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuznik, Nane C., Solozobova, Valeria, Lee, Irene I., Jung, Nicole, Yang, Linxiao, Nienhaus, Karin, Ntim, Emmanuel A., Rottenberg, Jaice T., Muhle-Goll, Claudia, Kumar, Amrish Rajendra, Peravali, Ravindra, Gräßle, Simone, Gourain, Victor, Deville, Célia, Cato, Laura, Neeb, Antje, Dilger, Marco, Cramer von Clausbruch, Christina A., Weiss, Carsten, Kieffer, Bruno, Nienhaus, G. Ulrich, Brown, Myles, Bräse, Stefan, Cato, Andrew C.B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036123/
https://www.ncbi.nlm.nih.gov/pubmed/35479411
http://dx.doi.org/10.1016/j.isci.2022.104175

Ejemplares similares

Ejemplares similares