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Silencing ATF3 Might Delay TBHP-Induced Intervertebral Disc Degeneration by Repressing NPC Ferroptosis, Apoptosis, and ECM Degradation

Intervertebral disc degeneration (IDD), being the predominant root cause of lower back pain, has led to an enormous socioeconomic burden in the world. Ferroptosis is an iron-dependent nonapoptotic and nonpyroptotic programmed cell death associated with an increase in reactive oxygen species (ROS), w...

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Detalles Bibliográficos
Autores principales: Li, Yongjin, Pan, Dayu, Wang, Xuke, Huo, Zhenxin, Wu, Xiaojing, Li, Jianhua, Cao, Jiasong, Xu, Haiwei, Du, Lilong, Xu, Baoshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036167/
https://www.ncbi.nlm.nih.gov/pubmed/35480873
http://dx.doi.org/10.1155/2022/4235126

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