Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature

Primary cutaneous CD30+ lymphoproliferative disorders include primary cutaneous anaplastic large cell lymphoma (pcALCL) and lymphomatoid papulosis. The prognosis of the disease is usually excellent but, in a minority of cases, it presents with extracutaneous involvement and aggressive behavior. The...

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Autores principales: Guarnera, Luca, Meconi, Federico, Pocci, Marco, Esposito, Fabiana, Rizzo, Manuela, Rapisarda, Vito Mario, Zizzari, Annagiulia, Di Raimondo, Cosimo, Pupo, Livio, Anemona, Lucia, Cantonetti, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036212/
https://www.ncbi.nlm.nih.gov/pubmed/35466174
http://dx.doi.org/10.3390/hematolrep14020010
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author Guarnera, Luca
Meconi, Federico
Pocci, Marco
Esposito, Fabiana
Rizzo, Manuela
Rapisarda, Vito Mario
Zizzari, Annagiulia
Di Raimondo, Cosimo
Pupo, Livio
Anemona, Lucia
Cantonetti, Maria
author_facet Guarnera, Luca
Meconi, Federico
Pocci, Marco
Esposito, Fabiana
Rizzo, Manuela
Rapisarda, Vito Mario
Zizzari, Annagiulia
Di Raimondo, Cosimo
Pupo, Livio
Anemona, Lucia
Cantonetti, Maria
author_sort Guarnera, Luca
collection PubMed
description Primary cutaneous CD30+ lymphoproliferative disorders include primary cutaneous anaplastic large cell lymphoma (pcALCL) and lymphomatoid papulosis. The prognosis of the disease is usually excellent but, in a minority of cases, it presents with extracutaneous involvement and aggressive behavior. The case we present—relapsed after surgical excision, immunosuppressive therapy, and conventional chemotherapy—is the first one treated with Autologous Stem Cell transplant followed by Brentuximab Vedotin consolidation, a scheme already used for high risk Hodgkin Lymphoma.
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spelling pubmed-90362122022-04-26 Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature Guarnera, Luca Meconi, Federico Pocci, Marco Esposito, Fabiana Rizzo, Manuela Rapisarda, Vito Mario Zizzari, Annagiulia Di Raimondo, Cosimo Pupo, Livio Anemona, Lucia Cantonetti, Maria Hematol Rep Case Report Primary cutaneous CD30+ lymphoproliferative disorders include primary cutaneous anaplastic large cell lymphoma (pcALCL) and lymphomatoid papulosis. The prognosis of the disease is usually excellent but, in a minority of cases, it presents with extracutaneous involvement and aggressive behavior. The case we present—relapsed after surgical excision, immunosuppressive therapy, and conventional chemotherapy—is the first one treated with Autologous Stem Cell transplant followed by Brentuximab Vedotin consolidation, a scheme already used for high risk Hodgkin Lymphoma. MDPI 2022-03-23 /pmc/articles/PMC9036212/ /pubmed/35466174 http://dx.doi.org/10.3390/hematolrep14020010 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Guarnera, Luca
Meconi, Federico
Pocci, Marco
Esposito, Fabiana
Rizzo, Manuela
Rapisarda, Vito Mario
Zizzari, Annagiulia
Di Raimondo, Cosimo
Pupo, Livio
Anemona, Lucia
Cantonetti, Maria
Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature
title Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature
title_full Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature
title_fullStr Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature
title_full_unstemmed Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature
title_short Aggressive Primary Cutaneous Anaplastic T-Cell Lymphoma Successfully Treated with Autologous Stem Cell Transplant and Brentuximab Vedotin Consolidation: Case Report and Review of the Literature
title_sort aggressive primary cutaneous anaplastic t-cell lymphoma successfully treated with autologous stem cell transplant and brentuximab vedotin consolidation: case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036212/
https://www.ncbi.nlm.nih.gov/pubmed/35466174
http://dx.doi.org/10.3390/hematolrep14020010
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