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HexA-Enzyme Coated Polymer Nanoparticles for the Development of a Drug-Delivery System in the Treatment of Sandhoff Lysosomal Storage Disease

Lysosomal storage disorders (LSDs) are a set of metabolic diseases caused by mutations in genes that are in charge of the production of lysosomal enzymes, resulting in the buildup of non-degraded substrates and the consequent systemic damage that mainly involves the Central Nervous System (CNS). One...

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Detalles Bibliográficos
Autores principales:	Calzoni, Eleonora, Cesaretti, Alessio, Montegiove, Nicolò, Di Michele, Alessandro, Pellegrino, Roberto Maria, Emiliani, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036261/ https://www.ncbi.nlm.nih.gov/pubmed/35466219 http://dx.doi.org/10.3390/jfb13020037

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