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Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit
Anorectal malignant melanoma is a rare culprit of malignancies in the anorectal region. With a presentation that mimics the vastly more common colorectal tumours, clinical misdiagnosis and diagnostic delays often occur, contributing to a dismal prognosis. The authors report a case of metastatic anor...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036300/ https://www.ncbi.nlm.nih.gov/pubmed/35466191 http://dx.doi.org/10.3390/diseases10020021 |
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author | Galante, Joao Adeleke, Sola Parkar, Rosemeen Bagla, Nipin Edwards, Albert Boussios, Stergios Raman, Rakesh |
author_facet | Galante, Joao Adeleke, Sola Parkar, Rosemeen Bagla, Nipin Edwards, Albert Boussios, Stergios Raman, Rakesh |
author_sort | Galante, Joao |
collection | PubMed |
description | Anorectal malignant melanoma is a rare culprit of malignancies in the anorectal region. With a presentation that mimics the vastly more common colorectal tumours, clinical misdiagnosis and diagnostic delays often occur, contributing to a dismal prognosis. The authors report a case of metastatic anorectal malignant melanoma presenting as seizures. Though our standard diagnostic pathway for suspected anorectal malignancies was followed, and despite the patient having computerized tomography (CT) of the head earlier, this presentation nonetheless led to a prolongation of time needed to reach histological diagnosis and delay in commencing definitive treatment. It also highlights the paucity of research into the pathophysiology and management of this infrequent but aggressive disease, and the need for raising awareness about this condition to the medical community so that it is considered as a plausible differential diagnosis from the outset and diagnostic pathways adjusted accordingly. |
format | Online Article Text |
id | pubmed-9036300 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90363002022-04-26 Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit Galante, Joao Adeleke, Sola Parkar, Rosemeen Bagla, Nipin Edwards, Albert Boussios, Stergios Raman, Rakesh Diseases Case Report Anorectal malignant melanoma is a rare culprit of malignancies in the anorectal region. With a presentation that mimics the vastly more common colorectal tumours, clinical misdiagnosis and diagnostic delays often occur, contributing to a dismal prognosis. The authors report a case of metastatic anorectal malignant melanoma presenting as seizures. Though our standard diagnostic pathway for suspected anorectal malignancies was followed, and despite the patient having computerized tomography (CT) of the head earlier, this presentation nonetheless led to a prolongation of time needed to reach histological diagnosis and delay in commencing definitive treatment. It also highlights the paucity of research into the pathophysiology and management of this infrequent but aggressive disease, and the need for raising awareness about this condition to the medical community so that it is considered as a plausible differential diagnosis from the outset and diagnostic pathways adjusted accordingly. MDPI 2022-04-08 /pmc/articles/PMC9036300/ /pubmed/35466191 http://dx.doi.org/10.3390/diseases10020021 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Galante, Joao Adeleke, Sola Parkar, Rosemeen Bagla, Nipin Edwards, Albert Boussios, Stergios Raman, Rakesh Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit |
title | Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit |
title_full | Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit |
title_fullStr | Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit |
title_full_unstemmed | Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit |
title_short | Metastatic Anorectal Melanoma Presenting as Seizures: An Infrequent Culprit |
title_sort | metastatic anorectal melanoma presenting as seizures: an infrequent culprit |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036300/ https://www.ncbi.nlm.nih.gov/pubmed/35466191 http://dx.doi.org/10.3390/diseases10020021 |
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