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Albumin and interferon-β fusion protein serves as an effective vaccine adjuvant to enhance antigen-specific CD8+ T cell-mediated antitumor immunity
BACKGROUND: Type I interferons (IFN) promote dendritic cells maturation and subsequently enhance generation of antigen-specific CD8 +T cell for the control of tumor. Using type I interferons as an adjuvant to vaccination could prove to be a potent strategy. However, type I interferons have a short h...
Autores principales: | Tseng, Ssu-Hsueh, Cheng, Max A, Farmer, Emily, Ferrall, Louise, Kung, Yu Jui, Lam, Brandon, Lim, Ling, Wu, T-C, Hung, Chien-Fu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036441/ https://www.ncbi.nlm.nih.gov/pubmed/35459734 http://dx.doi.org/10.1136/jitc-2021-004342 |
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