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Coarse-Grained Simulations Suggest Potential Competing Roles of Phosphoinositides and Amphipathic Helix Structures in Membrane Curvature Sensing of the AP180 N-Terminal Homology Domain

[Image: see text] The generation and sensing of membrane curvature by proteins has become of increasing interest to researchers with multiple mechanisms, from hydrophobic insertion to protein crowding, being identified. However, the role of charged lipids in the membrane curvature-sensing process is...

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Detalles Bibliográficos
Autores principales:	Belessiotis-Richards, Alexis, Larsen, Andreas H., Higgins, Stuart G., Stevens, Molly M., Alexander-Katz, Alfredo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036517/ https://www.ncbi.nlm.nih.gov/pubmed/35394774 http://dx.doi.org/10.1021/acs.jpcb.2c00239

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