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One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment

In this study, we found a green method to obtain aryl nitriles from aromatic aldehyde in water. This simple process was modified from a conventional method. Compared with those approaches, we used water as the solvent instead of harmful chemical reagents. In this one-pot conversion, we got twenty-fi...

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Detalles Bibliográficos
Autores principales: Lin, Hongyan, Zhou, Ziling, Ma, Xiaopeng, Chen, Qingqing, Han, Hongwei, Wang, Xiaoming, Qi, Jinliang, Yang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036638/
https://www.ncbi.nlm.nih.gov/pubmed/35479036
http://dx.doi.org/10.1039/d1ra03559b
Descripción
Sumario:In this study, we found a green method to obtain aryl nitriles from aromatic aldehyde in water. This simple process was modified from a conventional method. Compared with those approaches, we used water as the solvent instead of harmful chemical reagents. In this one-pot conversion, we got twenty-five aryl nitriles conveniently with pollution to the environment being minimized. Furthermore, we confirmed the reaction mechanism by capturing the intermediates, aldoximes.