Cargando…

Discovery of quinolone derivatives as antimycobacterial agents

Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis (M. tuberculosis), is an important public health issue. Current first-line drugs administered to TB patients have been in use for over 40 years, whereas second-line drugs display strong side effects and poor compliance. Ad...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Kun-Lin, Teng, Fei, Xiong, Lu, Li, Xiao, Gao, Chao, Yu, Luo-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036655/ https://www.ncbi.nlm.nih.gov/pubmed/35479020 http://dx.doi.org/10.1039/d0ra09250a

Ejemplares similares

Synthesis of N-substituted 2-[(1E)-alkenyl]-4-(1H)-quinolone derivatives as antimycobacterial agents against non-tubercular mycobacteria
por: Wube, Abraham A., et al.
Publicado: (2011)

Synthesis and biological evaluation of novel quinolone derivatives dual targeting histone deacetylase and tubulin polymerization as antiproliferative agents
por: Wang, Xuan, et al.
Publicado: (2018)

Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones
por: Wube, Abraham A., et al.
Publicado: (2011)

Quinolone antibiotics
por: Pham, Thu D. M., et al.
Publicado: (2019)

Pyridine appended 2-hydrazinylthiazole derivatives: design, synthesis, in vitro and in silico antimycobacterial studies
por: Matsa, Ramkishore, et al.
Publicado: (2022)

Synthesis and Discovery of Ligustrazine–Heterocycle Derivatives as Antitumor Agents
por: Ma, Shitang, et al.
Publicado: (2022)

Discovery of Novel Thiophene-arylamide Derivatives as DprE1 Inhibitors with Potent Antimycobacterial Activities
por: Wang, Pengxu, et al.
Publicado: (2021)

In-silico Metabolome Target Analysis Towards PanC-based Antimycobacterial Agent Discovery
por: Khoshkholgh-Sima, Baharak, et al.
Publicado: (2015)

Ion Transport Modulators as Antimycobacterial Agents
por: Mitini-Nkhoma, Steven C., et al.
Publicado: (2020)

Therapeutic Potential of Curcumin as an Antimycobacterial Agent
por: Barua, Nilakshi, et al.
Publicado: (2021)

Design, Synthesis, and Biological Evaluation of Novel Thiazolidinone-Containing Quinoxaline-1,4-di-N-oxides as Antimycobacterial and Antifungal Agents
por: Zhang, Heying, et al.
Publicado: (2020)

Inhibiting quinolone biosynthesis of Burkholderia
por: Prothiwa, Michaela, et al.
Publicado: (2021)

Design, synthesis and biological evaluation of benzo-[d]-imidazo-[2,1-b]-thiazole and imidazo-[2,1-b]-thiazole carboxamide triazole derivatives as antimycobacterial agents
por: Chitti, Surendar, et al.
Publicado: (2022)

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents
por: Maafi, Negar, et al.
Publicado: (2021)

Discovery and preliminary SAR of 14-aryloxy-andrographolide derivatives as antibacterial agents with immunosuppressant activity
por: Li, Feng, et al.
Publicado: (2018)

Editorial: Antimycobacterial drug discovery: Molecular therapeutics and target identification
por: Gunosewoyo, Hendra, et al.
Publicado: (2022)

Novel Sulfamethoxazole Ureas and Oxalamide as Potential Antimycobacterial Agents
por: Krátký, Martin, et al.
Publicado: (2017)

Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents
por: Wijaya, Viriyanata, et al.
Publicado: (2022)

Acetylene containing 2-(2-hydrazinyl)thiazole derivatives: design, synthesis, and in vitro and in silico evaluation of antimycobacterial activity against Mycobacterium tuberculosis
por: Maganti, Lakshmi Haritha Bharathi, et al.
Publicado: (2022)

Synthesis and Antimycobacterial Activity of 2,5-Disubstituted and 1,2,5-Trisubstituted Benzimidazoles
por: Jiménez-Juárez, Rogelio, et al.
Publicado: (2020)

Synthesis, computational studies, antimycobacterial and antibacterial properties of pyrazinoic acid–isoniazid hybrid conjugates
por: Panda, Siva S., et al.
Publicado: (2019)

Discovery of 4-nitro-3-phenylisoxazole derivatives as potent antibacterial agents derived from the studies of [3 + 2] cycloaddition
por: Zhang, Yan, et al.
Publicado: (2022)

Identification of a new series of benzothiazinone derivatives with excellent antitubercular activity and improved pharmacokinetic profiles
por: Xiong, Lu, et al.
Publicado: (2018)

Design, Synthesis and Evaluation of N-pyrazinylbenzamides as Potential Antimycobacterial Agents
por: Zitko, Jan, et al.
Publicado: (2018)

Targeting Energy Metabolism in Mycobacterium tuberculosis, a New Paradigm in Antimycobacterial Drug Discovery
por: Bald, Dirk, et al.
Publicado: (2017)

Combatting AMR: photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity
por: Smith, Nichola A., et al.
Publicado: (2017)

Synthesis of Quinolones and Zwitterionic Quinolonate Derivatives with Broad-Spectrum Antibiotic Activity
por: Suay-García, Beatriz, et al.
Publicado: (2022)

A thiochromenone antibiotic derived from the Pseudomonas quinolone signal selectively targets the Gram-negative pathogen Moraxella catarrhalis
por: Szamosvári, Dávid, et al.
Publicado: (2019)

In Silico Studies of Quinoxaline-2-Carboxamide 1,4-di-N-Oxide Derivatives as Antimycobacterial Agents
por: Radwan, Awwad A., et al.
Publicado: (2014)

Design and synthesis of novel Imidazo[2,1-b]thiazole derivatives as potent antiviral and antimycobacterial agents
por: Gürsoy, Elif, et al.
Publicado: (2020)

Synthesis and Antimycobacterial Activity of 2-(Phenylthio) benzoylarylhydrazone Derivatives
por: Almasirad, Ali, et al.
Publicado: (2011)

Antituberculosis: Synthesis and Antimycobacterial Activity of Novel Benzimidazole Derivatives
por: Keng Yoon, Yeong, et al.
Publicado: (2013)

Discovery of novel isatin-based thiosemicarbazones: synthesis, antibacterial, antifungal, and antimycobacterial screening
por: Hassan, Maryam, et al.
Publicado: (2020)

Editorial: Antimycobacterial drug discovery: molecular therapeutics and target identification, Volume II
por: Gunosewoyo, Hendra, et al.
Publicado: (2023)

Quinolone Antimicrobial Agents, 3rd Edition
por: Anderson, Gregory J.
Publicado: (2004)

A robust iron catalyst for the selective hydrogenation of substituted (iso)quinolones
por: Sahoo, Basudev, et al.
Publicado: (2018)

Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents
por: Kapp, Erika, et al.
Publicado: (2017)

Bibliometric Review on New Possibilities of Antimycobacterial Agents: Exploring Siderophore Desferrioxamine’s Applications as an Antimicrobial Agent
por: de Oliveira, Patrícia Vieira, et al.
Publicado: (2023)

In Vitro and In Silico Biological Studies of 4-Phenyl-2-quinolone (4-PQ) Derivatives as Anticancer Agents
por: Chen, Yi-Fong, et al.
Publicado: (2023)

Correction: A robust iron catalyst for the selective hydrogenation of substituted (iso)quinolones
por: Sahoo, Basudev, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_a8k6rsfti8o6stibts4qktudl0