Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions

The development of Friedel–Crafts alkylations with alcohols under continuous-flow conditions using heterogeneous catalysts is reported. The reactivities and durabilities of the examined catalysts were systematically investigated, which showed that montmorillonite clay is the best catalyst for these...

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Autores principales: Masuda, Koichiro, Okamoto, Yukiko, Onozawa, Shun-ya, Koumura, Nagatoshi, Kobayashi, Shū
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036667/
https://www.ncbi.nlm.nih.gov/pubmed/35479054
http://dx.doi.org/10.1039/d1ra04005g
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author Masuda, Koichiro
Okamoto, Yukiko
Onozawa, Shun-ya
Koumura, Nagatoshi
Kobayashi, Shū
author_facet Masuda, Koichiro
Okamoto, Yukiko
Onozawa, Shun-ya
Koumura, Nagatoshi
Kobayashi, Shū
author_sort Masuda, Koichiro
collection PubMed
description The development of Friedel–Crafts alkylations with alcohols under continuous-flow conditions using heterogeneous catalysts is reported. The reactivities and durabilities of the examined catalysts were systematically investigated, which showed that montmorillonite clay is the best catalyst for these reactions. A high turnover frequency of 9.0 × 10(2) h(−1) was recorded under continuous-flow conditions, and the continuous operation was successfully maintained over one week.
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spelling pubmed-90366672022-04-26 Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions Masuda, Koichiro Okamoto, Yukiko Onozawa, Shun-ya Koumura, Nagatoshi Kobayashi, Shū RSC Adv Chemistry The development of Friedel–Crafts alkylations with alcohols under continuous-flow conditions using heterogeneous catalysts is reported. The reactivities and durabilities of the examined catalysts were systematically investigated, which showed that montmorillonite clay is the best catalyst for these reactions. A high turnover frequency of 9.0 × 10(2) h(−1) was recorded under continuous-flow conditions, and the continuous operation was successfully maintained over one week. The Royal Society of Chemistry 2021-07-13 /pmc/articles/PMC9036667/ /pubmed/35479054 http://dx.doi.org/10.1039/d1ra04005g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Masuda, Koichiro
Okamoto, Yukiko
Onozawa, Shun-ya
Koumura, Nagatoshi
Kobayashi, Shū
Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
title Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
title_full Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
title_fullStr Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
title_full_unstemmed Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
title_short Development of highly efficient Friedel–Crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
title_sort development of highly efficient friedel–crafts alkylations with alcohols using heterogeneous catalysts under continuous-flow conditions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036667/
https://www.ncbi.nlm.nih.gov/pubmed/35479054
http://dx.doi.org/10.1039/d1ra04005g
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AT onozawashunya developmentofhighlyefficientfriedelcraftsalkylationswithalcoholsusingheterogeneouscatalystsundercontinuousflowconditions
AT koumuranagatoshi developmentofhighlyefficientfriedelcraftsalkylationswithalcoholsusingheterogeneouscatalystsundercontinuousflowconditions
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