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2′,3′,4′-Trihydroxychalcone changes estrogen receptor α regulation of genes and breast cancer cell proliferation by a reprogramming mechanism

BACKGROUND: Menopausal hormone therapy (MHT) is recommended for only five years to treat vasomotor symptoms and vulvovaginal atrophy because of safety concerns with long-term treatment. We investigated the ability of 2′,3′,4′-trihydroxychalcone (2′,3′,4′-THC) to modulate estrogen receptor (ER)-media...

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Detalles Bibliográficos
Autores principales:	Herber, Candice B., Yuan, Chaoshen, Chang, Anthony, Wang, Jen-Chywan, Cohen, Isaac, Leitman, Dale C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036729/ https://www.ncbi.nlm.nih.gov/pubmed/35468719 http://dx.doi.org/10.1186/s10020-022-00470-z

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