Angiopoietin2-mediated caveolin1 phosphorylation regulating transcytosis of renal tubular epithelial cell contributes to the occurrence of albuminuria under high glucose exposure

BACKGROUND: Microlbuminuria is the earliest clinical evidence of diabetic kidney disease (DKD) and contributes to the induction and/or progression of DKD. Previous studies have shown that increased expression of angiopoietin2 (ANGPT2) is correlated with an increase in albuminuria. However, the criti...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Yao, Junxia, Zhao, Yi, Su, Jinxuan, Ye, Jiajia, Wang, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036792/
https://www.ncbi.nlm.nih.gov/pubmed/35468852
http://dx.doi.org/10.1186/s12967-022-03388-6

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