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Reversing direct factor Xa or thrombin inhibitors: Factor V addition to prothrombin complex concentrate is beneficial in vitro

BACKGROUND: Prothrombin complex concentrate (PCC) is a human plasma‐derived mixture of partially purified vitamin K‐dependent coagulation factors (VKCF). Current therapeutic indication is treatment and perioperative prophylaxis of bleeding in acquired VKCF deficiency. Off‐label uses include treatmen...

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Detalles Bibliográficos
Autores principales:	Brinkman, Herm Jan M., Swieringa, Frauke, Zuurveld, Marleen, Veninga, Alicia, Brouns, Sanne L. N., Heemskerk, Johan W. M., Meijers, Joost C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036856/ https://www.ncbi.nlm.nih.gov/pubmed/35494506 http://dx.doi.org/10.1002/rth2.12699

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