Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction

A new series of pyrimido[1,2-b]indazoles bearing indolenine moieties was synthesized through a simple condensation reaction with up to 94% yield. The present method features the versatile formation of a pyrimidine ring with a broad range of substrates, great functional group compatibility and facile...

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Autores principales: Ramle, Abdul Qaiyum, Fei, Chee Chin, Tiekink, Edward R. T., Basirun, Wan Jefrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036913/
https://www.ncbi.nlm.nih.gov/pubmed/35481028
http://dx.doi.org/10.1039/d1ra04372b
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author Ramle, Abdul Qaiyum
Fei, Chee Chin
Tiekink, Edward R. T.
Basirun, Wan Jefrey
author_facet Ramle, Abdul Qaiyum
Fei, Chee Chin
Tiekink, Edward R. T.
Basirun, Wan Jefrey
author_sort Ramle, Abdul Qaiyum
collection PubMed
description A new series of pyrimido[1,2-b]indazoles bearing indolenine moieties was synthesized through a simple condensation reaction with up to 94% yield. The present method features the versatile formation of a pyrimidine ring with a broad range of substrates, great functional group compatibility and facile synthetic operation. The work offers opportunities in drug development as well as in materials science.
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spelling pubmed-90369132022-04-26 Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction Ramle, Abdul Qaiyum Fei, Chee Chin Tiekink, Edward R. T. Basirun, Wan Jefrey RSC Adv Chemistry A new series of pyrimido[1,2-b]indazoles bearing indolenine moieties was synthesized through a simple condensation reaction with up to 94% yield. The present method features the versatile formation of a pyrimidine ring with a broad range of substrates, great functional group compatibility and facile synthetic operation. The work offers opportunities in drug development as well as in materials science. The Royal Society of Chemistry 2021-07-14 /pmc/articles/PMC9036913/ /pubmed/35481028 http://dx.doi.org/10.1039/d1ra04372b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Ramle, Abdul Qaiyum
Fei, Chee Chin
Tiekink, Edward R. T.
Basirun, Wan Jefrey
Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction
title Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction
title_full Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction
title_fullStr Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction
title_full_unstemmed Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction
title_short Indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction
title_sort indoleninyl-substituted pyrimido[1,2-b]indazoles via a facile condensation reaction
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036913/
https://www.ncbi.nlm.nih.gov/pubmed/35481028
http://dx.doi.org/10.1039/d1ra04372b
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AT tiekinkedwardrt indoleninylsubstitutedpyrimido12bindazolesviaafacilecondensationreaction
AT basirunwanjefrey indoleninylsubstitutedpyrimido12bindazolesviaafacilecondensationreaction

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