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Live, Genetically Attenuated, Cold-Chain-Free Cholera Vaccine—A Research and Development Journey: Light at the End of a Long Tunnel

Cholera, a diarrheal disease caused by Vibrio cholerae (V. cholerae) O139 and O1 strains, remains a public health problem. The existing World Health Organization (WHO)-licenced, killed, multiple-dose oral cholera vaccines demand ‘cold-chain supply’ at 2 °C–8 °C. Therefore, a live, single-dose, cold-...

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Detalles Bibliográficos
Autores principales: RAVICHANDRAN, Manickam, TEW, Hui Xian, PRABHAKARAN, Guruswamy, PARASURAMAN, Subramani, NORAZMI, Mohd Nor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Penerbit Universiti Sains Malaysia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036929/
https://www.ncbi.nlm.nih.gov/pubmed/35528817
http://dx.doi.org/10.21315/mjms2022.29.2.1